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Binding and release of iron by gel-encapsulated human transferrin: Evidence for a conformational search
Human transferrin is a single-chain bilobal protein with each of the two similar but not identical lobes in turn composed of two domains. Each lobe may assume one of two stable structural conformations, open or closed, determined by a rigid rotation of the domains with respect to each other. In solu...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153007/ https://ncbi.nlm.nih.gov/pubmed/12486226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262526399 |
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