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Binding and release of iron by gel-encapsulated human transferrin: Evidence for a conformational search

Human transferrin is a single-chain bilobal protein with each of the two similar but not identical lobes in turn composed of two domains. Each lobe may assume one of two stable structural conformations, open or closed, determined by a rigid rotation of the domains with respect to each other. In solu...

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Detaylı Bibliyografya
Asıl Yazarlar: Navati, Mahantesh S., Samuni, Uri, Aisen, Philip, Friedman, Joel M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC153007/
https://ncbi.nlm.nih.gov/pubmed/12486226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262526399
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