Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease

Emerging evidence points to reactive glia as a pivotal factor in Parkinson’s disease (PD) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned mouse model of basal ganglia injury, but whether astrocytes and microglia activation may exacerbate dopaminergic (DAergic) neuron demise and/or c...

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Bibliografski detalji
Glavni autori: L’Episcopo, F., Tirolo, C., Testa, N., Caniglia, S., Morale, M.C., Cossetti, C., D’Adamo, P., Zardini, E., Andreoni, L., Ihekwaba, A.E.C., Serra, P.A., Franciotta, D., Martino, G., Pluchino, S., Marchetti, B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558878/
https://ncbi.nlm.nih.gov/pubmed/21056667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.10.023
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