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Alteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing Brain

Studies on therapeutic drug disposition in humans have shown significant alterations as the result of pregnancy. However, it is not known whether pesticide metabolic capacity changes throughout pregnancy, which could affect exposure of the developing brain. We sought to determine the effect of pregn...

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Autori principali: Fortin, Marie C., Aleksunes, Lauren M., Richardson, Jason R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558862/
https://ncbi.nlm.nih.gov/pubmed/23223497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.049395
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