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Regulation of Hepatic Phase II Metabolism in Pregnant Mice

Phase II enzymes, including Ugts, Sults, and Gsts, are critical for the disposition and detoxification of endo- and xenobiotics. In this study, the mRNA and protein expression of major phase II enzymes, as well as key regulatory transcription factors, were quantified in livers of time-matched pregna...

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Autors principals: Wen, Xia, Donepudi, Ajay C., Thomas, Paul E., Slitt, Angela L., King, Roberta S., Aleksunes, Lauren M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533409/
https://ncbi.nlm.nih.gov/pubmed/23055538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.199034
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