Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice

Pregnancy-induced changes in drug pharmacokinetics can be explained by changes in expression of drug-metabolizing enzymes and transporters and/or normal physiology. In this study, we determined gestational age-dependent expression profiles for all metabolic enzyme and transporter genes in the matern...

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Main Authors: Shuster, Diana L., Bammler, Theo K., Beyer, Richard P., MacDonald, James W., Tsai, Jesse M., Farin, Frederico M., Hebert, Mary F., Thummel, Kenneth E., Mao, Qingcheng
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2013
Teme:
Special Section on Drug Metabolizing Enzymes and Transporters in Pregnancy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558854/
https://ncbi.nlm.nih.gov/pubmed/23175668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.049718
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