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Maternal-Fetal Disposition of Glyburide in Pregnant Mice Is Dependent on Gestational Age
Gestational diabetes mellitus is a major complication of human pregnancy. The oral clearance (CL) of glyburide, an oral antidiabetic drug, increases 2-fold in pregnant women during late gestation versus nonpregnant controls. In this study, we examined gestational age–dependent changes in maternal-fe...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109496/ https://ncbi.nlm.nih.gov/pubmed/24898265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.213470 |
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