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Selective Effects of a Morphine Conjugate Vaccine on Heroin and Metabolite Distribution and Heroin-Induced Behaviors in Rats

Morphine conjugate vaccines have effectively reduced behavioral effects of heroin in rodents and primates. To better understand how these effects are mediated, heroin and metabolite distribution studies were performed in rats in the presence and absence of vaccination. In non-vaccinated rats 6-monoa...

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Detalhes bibliográficos
Main Authors: Raleigh, M.D., Pravetoni, M., Harris, A.C., Birnbaum, A.K., Pentel, P.R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558830/
https://ncbi.nlm.nih.gov/pubmed/23220743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.201194
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