Mechanism of the Antiproliferative Activity of Some Naphthalene Diimide G-Quadruplex Ligands

G-quadruplexes are higher-order nucleic acid structures that can form in G-rich telomeres and promoter regions of oncogenes. Telomeric quadruplex stabilization by small molecules can lead to telomere uncapping, followed by DNA damage response and senescence, as well as chromosomal fusions leading to...

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Detaylı Bibliyografya
Asıl Yazarlar: Hampel, Sonja M., Pepe, Antonella, Greulich-Bode, Karin M., Malhotra, Sanjay V., Reszka, Anthony P., Veith, Sebastian, Boukamp, Petra, Neidle, Stephen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2013
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558810/
https://ncbi.nlm.nih.gov/pubmed/23188717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.081075
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