Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G‐quadruplex in K(+) Buffer

Selective G‐quadruplex ligands offer great promise for the development of anti‐cancer therapies. A novel series of divalent cationic naphthalene diimide ligands that selectively bind to the hybrid form of the human telomeric G‐quadruplex in K(+) buffer are described herein. We demonstrate that an im...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Street, Steven T. G., Chin, Donovan N., Hollingworth, Gregory J., Berry, Monica, Morales, Juan C., Galan, M. Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485019/
https://ncbi.nlm.nih.gov/pubmed/28257554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201700140
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