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Noncompetitive, Voltage-Dependent NMDA Receptor Antagonism by Hydrophobic Anions

NMDA receptor (NMDAR) antagonists are dissociative anesthetics, drugs of abuse, and are of therapeutic interest in neurodegeneration and neuropsychiatric disease. Many well-known NMDAR antagonists are positively charged, voltage-dependent channel blockers. We recently showed that the hydrophobic ani...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Linsenbardt, Andrew J., Chisari, Mariangela, Yu, Andrew, Shu, Hong-Jin, Zorumski, Charles F., Mennerick, Steven
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558806/
https://ncbi.nlm.nih.gov/pubmed/23144238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.081794
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