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Noncompetitive, Voltage-Dependent NMDA Receptor Antagonism by Hydrophobic Anions
NMDA receptor (NMDAR) antagonists are dissociative anesthetics, drugs of abuse, and are of therapeutic interest in neurodegeneration and neuropsychiatric disease. Many well-known NMDAR antagonists are positively charged, voltage-dependent channel blockers. We recently showed that the hydrophobic ani...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558806/ https://ncbi.nlm.nih.gov/pubmed/23144238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.081794 |
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