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Mitogen-Activated Protein Kinase Feedback Phosphorylation Regulates MEK1 Complex Formation and Activation during Cellular Adhesion

Cell adhesion and spreading depend on activation of mitogen-activated kinase, which in turn is regulated both by growth factor and integrin signaling. Growth factors, such as epidermal growth factor, are capable of activating Ras and Raf, but integrin signaling is required to couple Raf to MEK and M...

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Détails bibliographiques
Auteurs principaux: Eblen, Scott T., Slack-Davis, Jill K., Tarcsafalvi, Adel, Parsons, J. Thomas, Weber, Michael J., Catling, Andrew D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC355870/
https://ncbi.nlm.nih.gov/pubmed/14993270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2308-2317.2004
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