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PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
Activation of the Ras–MAPK signal transduction pathway is necessary for biological responses both to growth factors and ECM. Here, we provide evidence that phosphorylation of S298 of MAPK kinase 1 (MEK1) by p21-activated kinase (PAK) is a site of convergence for integrin and growth factor signaling....
Tallennettuna:
| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
2003
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172784/ https://ncbi.nlm.nih.gov/pubmed/12876277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200212141 |
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