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Inhibition of the Jun N-Terminal Protein Kinase Pathway by SHIP-1, a Lipid Phosphatase That Interacts with the Adaptor Molecule Dok-3

Dok-3 is a Dok-related adaptor expressed in B cells and macrophages. Previously, we reported that Dok-3 is an inhibitor of B-cell activation in A20 B cells and that it associates with SHIP-1, a 5′ inositol-specific lipid phosphatase, as well as Csk, a negative regulator of Src kinases. Here, we demo...

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Detalhes bibliográficos
Main Authors: Robson, Jeffrey D., Davidson, Dominique, Veillette, André
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC355862/
https://ncbi.nlm.nih.gov/pubmed/14993273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2332-2343.2004
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