Phosphorylation-Dependent Regulation of T-Cell Activation by PAG/Cbp, a Lipid Raft-Associated Transmembrane Adaptor

PAG/Cbp (hereafter named PAG) is a transmembrane adaptor molecule found in lipid rafts. In resting human T cells, PAG is tyrosine phosphorylated and associated with Csk, an inhibitor of Src-related protein tyrosine kinases. These modifications are rapidly lost in response to T-cell receptor (TCR) st...

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Detalhes bibliográficos
Main Authors: Davidson, Dominique, Bakinowski, Marcin, Thomas, Matthew L., Horejsi, Vaclav, Veillette, André
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149484/
https://ncbi.nlm.nih.gov/pubmed/12612075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.6.2017-2028.2003
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