Mutations Causing Childhood Ataxia with Central Nervous System Hypomyelination Reduce Eukaryotic Initiation Factor 2B Complex Formation and Activity

Childhood ataxia with central nervous system hypomyelination (CACH), or vanishing white matter leukoencephalopathy (VWM), is a fatal brain disorder caused by mutations in eukaryotic initiation factor 2B (eIF2B). eIF2B is essential for protein synthesis and regulates translation in response to cellul...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Richardson, Jonathan P., Mohammad, Sarah S., Pavitt, Graham D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Gene Expression
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC355856/
https://ncbi.nlm.nih.gov/pubmed/14993275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2352-2363.2004
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items