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Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation
BACKGROUND: In sickle cell disease (SCD), the mitogen-activated protein kinase (MAPK) ERK1/2 is constitutively active and can be inducible by agonist-stimulation only in sickle but not in normal human red blood cells (RBCs). ERK1/2 is involved in activation of ICAM-4-mediated sickle RBC adhesion to...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558407/ https://ncbi.nlm.nih.gov/pubmed/23286773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1559-0275-10-1 |
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