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De novo assembly of bacterial genomes from single cells
Whole genome amplification by the multiple displacement amplification (MDA) method allows sequencing of genomes from single cells of bacteria that cannot be cultured. However, genome assembly is challenging because of highly non-uniform read coverage generated by MDA. We describe an improved assembl...
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| 主要な著者: | , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558281/ https://ncbi.nlm.nih.gov/pubmed/21926975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1966 |
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