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Global analysis of disease-related DNA sequence variation in 10 healthy individuals: Implications for whole genome-based clinical diagnostics

BACKGROUND: Understanding how sequence variants within healthy genomes are distributed with respect to ethnicity and disease-implicated genes is an essential first step toward establishing baselines for personalized genomic medicine. METHODS: In this study, we present an analysis of 10 genomes from...

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Autors principals: Moore, Barry, Hu, Hao, Singleton, Marc, De La Vega, Francisco M., Reese, Martin G., Yandell, Mark
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558030/
https://ncbi.nlm.nih.gov/pubmed/21325948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GIM.0b013e31820ed321
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