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PROFILING GLYCOL-SPLIT HEPARINS BY HPLC/MS ANALYSIS OF THEIR HEPARINASE-GENERATED OLIGOSACCHARIDES()

Glycol-split (gs) heparins, obtained by periodate oxidation / borohydride reduction of heparin currently used as anticoagulant and antithrombotic drug, are arousing increasing interest in anti-cancer and anti-inflammation therapies. These new medical uses are favored by the loss of anticoagulant act...

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Main Authors: Alekseeva, Anna, Casu, Benito, Torri, Giangiacomo, Pierro, Sabrina, Naggi, Annamaria
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557783/
https://ncbi.nlm.nih.gov/pubmed/23201389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.11.011
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