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PROFILING GLYCOL-SPLIT HEPARINS BY HPLC/MS ANALYSIS OF THEIR HEPARINASE-GENERATED OLIGOSACCHARIDES()

Glycol-split (gs) heparins, obtained by periodate oxidation / borohydride reduction of heparin currently used as anticoagulant and antithrombotic drug, are arousing increasing interest in anti-cancer and anti-inflammation therapies. These new medical uses are favored by the loss of anticoagulant act...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alekseeva, Anna, Casu, Benito, Torri, Giangiacomo, Pierro, Sabrina, Naggi, Annamaria
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557783/
https://ncbi.nlm.nih.gov/pubmed/23201389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.11.011
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