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Structural features of glycol-split low-molecular-weight heparins and their heparin lyase-generated fragments

Periodate oxidation followed by borohydride reduction converts the well-known antithrombotics heparin and low-molecular weight heparins (LMWHs) into their “glycol-split” (gs) derivatives of the “reduced oxyheparin” (RO) type, some of which are currently being developed as potential anti-cancer and a...

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Detalhes bibliográficos
Main Authors: Alekseeva, Anna, Casu, Benito, Cassinelli, Giuseppe, Guerrini, Marco, Torri, Giangiacomo, Naggi, Annamaria
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925387/
https://ncbi.nlm.nih.gov/pubmed/24253408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-013-7446-4
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