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Complement component 3 inhibition by an antioxidant is neuroprotective after cerebral ischemia and reperfusion in mice

Oxidative stress after stroke is associated with the inflammatory system activation in the brain. The complement cascade, especially the degradation products of complement component 3, is a key inflammatory mediator of cerebral ischemia. We have shown that proinflammatory complement component 3 is i...

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Autors principals: Yang, Jiwon, Ahn, Hye-na, Chang, Minsun, Narasimhan, Purnima, Chan, Pak H., Song, Yun Seon
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557607/
https://ncbi.nlm.nih.gov/pubmed/23199288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12111
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