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Regulation of Mn-Superoxide Dismutase Activity and Neuroprotection by STAT3 in Mice after Cerebral Ischemia

Cerebral ischemia and reperfusion increase superoxide anions (O(2)(·−)) in brain mitochondria. Manganese superoxide dismutase (Mn-SOD; SOD2), a primary mitochondrial antioxidant enzyme, scavenges superoxide radicals and its overexpression provides neuroprotection. However, the regulatory mechanism o...

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Detaylı Bibliyografya
Asıl Yazarlar: Jung, Joo Eun, Kim, Gab Seok, Narasimhan, Purnima, Song, Yun Seon, Chan, Pak H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712132/
https://ncbi.nlm.nih.gov/pubmed/19474327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1110-09.2009
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