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Regulation of Mn-Superoxide Dismutase Activity and Neuroprotection by STAT3 in Mice after Cerebral Ischemia
Cerebral ischemia and reperfusion increase superoxide anions (O(2)(·−)) in brain mitochondria. Manganese superoxide dismutase (Mn-SOD; SOD2), a primary mitochondrial antioxidant enzyme, scavenges superoxide radicals and its overexpression provides neuroprotection. However, the regulatory mechanism o...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712132/ https://ncbi.nlm.nih.gov/pubmed/19474327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1110-09.2009 |
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