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Complement component 3 inhibition by an antioxidant is neuroprotective after cerebral ischemia and reperfusion in mice

Oxidative stress after stroke is associated with the inflammatory system activation in the brain. The complement cascade, especially the degradation products of complement component 3, is a key inflammatory mediator of cerebral ischemia. We have shown that proinflammatory complement component 3 is i...

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Detalhes bibliográficos
Main Authors: Yang, Jiwon, Ahn, Hye-na, Chang, Minsun, Narasimhan, Purnima, Chan, Pak H., Song, Yun Seon
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557607/
https://ncbi.nlm.nih.gov/pubmed/23199288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12111
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