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Characterization of the chemical reactivity and nephrotoxicity of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide, a potential reactive metabolite of trichloroethylene

N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine (NA-DCVC) has been detected in the urine of humans exposed to trichloroethylene and its related sulfoxide, N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide (NA-DCVCS), has been detected as hemoglobin adducts in blood of rats dosed with S-(1,2-dichloroviny...

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Detalhes bibliográficos
Main Authors: Irving, Roy M., Pinkerton, Marie E., Elfarra, Adnan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557599/
https://ncbi.nlm.nih.gov/pubmed/23253325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.12.002
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