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Mutagenicity of the Cysteine S-Conjugate Sulfoxides of Trichloroethylene and Tetrachloroethylene in the Ames Test
The nephrotoxicity and nephrocarcinogenicity of trichloroethylene (TCE) and tetrachloroethylene (PCE) are believed to be mediated primarily through the cysteine S-conjugate β-lyase-dependent bioactivation of the corresponding cysteine S-conjugate metabolites S-(1,2-dichlorovinyl)-L-cysteine (DCVC) a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631458/ https://ncbi.nlm.nih.gov/pubmed/23416178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2013.02.003 |
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