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Intra-tympanic delivery of short interfering RNA into the adult mouse cochlea

Trans-tympanic injection into the middle ear has long been the standard for local delivery of compounds in experimental studies. Here we demonstrate the advantages of the novel method of intra-tympanic injection through the otic bone for the delivery of compounds or siRNA into the adult mouse cochle...

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Bibliografiske detaljer
Main Authors: Oishi, Naoki, Chen, Fu-Quan, Zheng, Hong-Wei, Sha, Su-Hua
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557582/
https://ncbi.nlm.nih.gov/pubmed/23183031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2012.10.011
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