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Access to the Akuammiline Family of Alkaloids: Total Synthesis of (+)-Scholarisine A
The planning and implementation of an enantioselective total synthesis of (+)-scholarisine A is presented. Key tactics employed include a novel cyclization, consisting of a nitrile reduction coupled with concomitant addition of the resultant amine to an epoxide; a modified Fischer indolization; an o...
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Autores principales: | , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557466/ https://ncbi.nlm.nih.gov/pubmed/23268611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3111626 |
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