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Access to the Akuammiline Family of Alkaloids: Total Synthesis of (+)-Scholarisine A

The planning and implementation of an enantioselective total synthesis of (+)-scholarisine A is presented. Key tactics employed include a novel cyclization, consisting of a nitrile reduction coupled with concomitant addition of the resultant amine to an epoxide; a modified Fischer indolization; an o...

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Detalhes bibliográficos
Main Authors: Adams, Gregory L., Carroll, Patrick J., Smith, Amos B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557466/
https://ncbi.nlm.nih.gov/pubmed/23268611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3111626
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