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Total Synthesis of the Akuammiline Alkaloid Picrinine

[Image: see text] We report the first total synthesis of the complex akuammiline alkaloid picrinine, which was first isolated nearly five decades ago. Our synthetic approach features a concise assembly of the [3.3.1]-azabicyclic core, a key Fischer indolization reaction to forge the natural product’...

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Detalhes bibliográficos
Main Authors: Smith, Joel M., Moreno, Jesus, Boal, Ben W., Garg, Neil K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985766/
https://ncbi.nlm.nih.gov/pubmed/24597784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja501780w
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