PAPTi: A Peptide Aptamer Interference Toolkit for Perturbation of Protein-Protein Interaction Networks

Signaling proteins often form dynamic protein-protein interaction (PPI) complexes to achieve multi-functionality. Methods to abrogate a subset of PPI interfaces without depleting the full-length protein will be valuable for structure-function relationship annotations. Here, we describe the use of Pe...

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Hlavní autoři: Yeh, Johannes T. -H., Binari, Richard, Gocha, Tenzin, Dasgupta, Ramanuj, Perrimon, Norbert
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557448/
https://ncbi.nlm.nih.gov/pubmed/23362456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01156
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