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Oxidative Stress, Redox Signaling, and Metal Chelation in Anthracycline Cardiotoxicity and Pharmacological Cardioprotection

Significance: Anthracyclines (doxorubicin, daunorubicin, or epirubicin) rank among the most effective anticancer drugs, but their clinical usefulness is hampered by the risk of cardiotoxicity. The most feared are the chronic forms of cardiotoxicity, characterized by irreversible cardiac damage and c...

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Detalhes bibliográficos
Main Authors: Štěrba, Martin, Popelová, Olga, Vávrová, Anna, Jirkovský, Eduard, Kovaříková, Petra, Geršl, Vladimír, Šimůnek, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557437/
https://ncbi.nlm.nih.gov/pubmed/22794198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4795
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