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Daclizumab Therapy for Multiple Sclerosis
Daclizumab is a humanized monoclonal antibody of IgG1 subtype that binds to the Tac epitope on the interleukin-2 (IL-2) receptor α-chain (CD25), thus, effectively blocking the formation of the high-affinity IL-2 receptor. Because the high-affinity IL-2 receptor signaling promotes expansion of activa...
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| Natura: | Artigo |
| Lingua: | Inglês |
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Springer-Verlag
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557356/ https://ncbi.nlm.nih.gov/pubmed/23055048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-012-0147-4 |
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