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Daclizumab Therapy for Multiple Sclerosis

Daclizumab is a humanized monoclonal antibody of IgG1 subtype that binds to the Tac epitope on the interleukin-2 (IL-2) receptor α-chain (CD25), thus, effectively blocking the formation of the high-affinity IL-2 receptor. Because the high-affinity IL-2 receptor signaling promotes expansion of activa...

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Bibliografske podrobnosti
Glavni avtor: Bielekova, Bibiana
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557356/
https://ncbi.nlm.nih.gov/pubmed/23055048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-012-0147-4
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