Functional Consequences of a Novel Variant of PCSK1

BACKGROUND: Common single nucleotide polymorphisms (SNPs) in proprotein convertase subtilisin/kexin type 1 with modest effects on PC1/3 in vitro have been associated with obesity in five genome-wide association studies and with diabetes in one genome-wide association study. We here present a novel S...

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Main Authors: Pickett, Lindsay A., Yourshaw, Michael, Albornoz, Valeria, Chen, Zijun, Solorzano-Vargas, R. Sergio, Nelson, Stanley F., Martín, Martín G., Lindberg, Iris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557230/
https://ncbi.nlm.nih.gov/pubmed/23383060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055065
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