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PCSK1 Variants and Human Obesity

PCSK1 , encoding prohormone convertase 1/3 (PC1/3), was one of the first genes linked to monogenic early-onset obesity. PC1/3 is a protease involved in the biosynthetic processing of a variety of neuropeptides and prohormones in endocrine tissues. PC1/3 activity is essential for the activating cleav...

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Detalhes bibliográficos
Publicado no:Prog Mol Biol Transl Sci
Main Authors: Ramos-Molina, Bruno, Martin, Martin G., Lindberg, Iris
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082390/
https://ncbi.nlm.nih.gov/pubmed/27288825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2015.12.001
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