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PCSK1 Variants and Human Obesity
PCSK1 , encoding prohormone convertase 1/3 (PC1/3), was one of the first genes linked to monogenic early-onset obesity. PC1/3 is a protease involved in the biosynthetic processing of a variety of neuropeptides and prohormones in endocrine tissues. PC1/3 activity is essential for the activating cleav...
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| Publicado en: | Prog Mol Biol Transl Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6082390/ https://ncbi.nlm.nih.gov/pubmed/27288825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2015.12.001 |
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