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Functional analysis of PCSK2 coding variants: a founder effect in the Old Order Amish population

AIMS: In humans, noncoding variants of PCSK2, the gene encoding prohormone convertase 2 (PC2), have been previously associated with risk for and age of onset of type 2 diabetes (T2D). The aims of this study were to identify coding variants in PCSK2; to determine their possible association with gluco...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Diabetes Res Clin Pract
मुख्य लेखकों: Winters, Alexandra, Ramos-Molina, Bruno, Jarvela, Timothy S., Yerges-Armstrong, Laura, Pollin, Toni, Lindberg, Iris
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572827/
https://ncbi.nlm.nih.gov/pubmed/28719828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diabres.2017.06.023
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