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Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells
BACKGROUND: Palmitic acid, the most common saturated free fatty acid, has been implicated in ER (endoplasmic reticulum) stress-mediated apoptosis. This lipoapotosis is dependent, in part, on the upregulation of the activating transcription factor-4 (ATF4). To better understand the mechanisms by whic...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557202/ https://ncbi.nlm.nih.gov/pubmed/23339444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-9 |
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