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Repression of PKR Mediates Palmitate-Induced Apoptosis in HepG2 Cells through Bcl-2

In the present study we found that double-stranded RNA-dependent protein kinase (PKR) regulates the protein expression level and the phosphorylation of Bcl-2 and exploits an anti-apoptotic role in human hepatocellular carcinoma cells (HepG2). Saturated free fatty acids (FFAs), e.g. palmitate, have b...

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Detalhes bibliográficos
Main Authors: Yang, Xuerui, Chan, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664847/
https://ncbi.nlm.nih.gov/pubmed/19259124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2009.25
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