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Modulating the innate immune response by combinatorial engineering of endotoxin
Despite its highly inflammatory nature, LPS is a molecule with remarkable therapeutic potential. Lipid A is a glycolipid that serves as the hydrophobic anchor of LPS and constitutes a potent ligand of the Toll-like receptor (TLR)4/myeloid differentiation factor 2 receptor of the innate immune system...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557076/ https://ncbi.nlm.nih.gov/pubmed/23297218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218080110 |
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