tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma

Sequencing studies from several model systems have suggested that diverse and abundant small RNAs may be derived from tRNA, but the function of these molecules remains undefined. Here, we demonstrate that one such tRNA-derived fragment, cloned from human mature B cells and designated CU1276, in fact...

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Bibliografiska uppgifter
Huvudupphovsmän: Maute, Roy L., Schneider, Christof, Sumazin, Pavel, Holmes, Antony, Califano, Andrea, Basso, Katia, Dalla-Favera, Riccardo
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557069/
https://ncbi.nlm.nih.gov/pubmed/23297232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206761110
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