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Pathway of actin filament branch formation by Arp2/3 complex revealed by single-molecule imaging

Actin filament nucleation by actin-related protein (Arp) 2/3 complex is a critical process in cell motility and endocytosis, yet key aspects of its mechanism are unknown due to a lack of real-time observations of Arp2/3 complex through the nucleation process. Triggered by the verprolin homology, cen...

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Detalles Bibliográficos
Autores principales: Smith, Benjamin A., Daugherty-Clarke, Karen, Goode, Bruce L., Gelles, Jeff
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557048/
https://ncbi.nlm.nih.gov/pubmed/23292935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211164110
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