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GMF is a cofilin homologue that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation

Cell locomotion and endocytosis are powered by the rapid polymerization and turnover of branched actin filament networks nucleated by Arp2/3 complex [1]. While a large number of cellular factors have been identified that stimulate Arp2/3 complex-mediated actin nucleation, only a small number of stud...

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Autors principals: Gandhi, Meghal, Smith, Benjamin A., Bovellan, Miia, Paavilainen, Ville, Daugherty-Clarke, Karen, Gelles, Jeff, Lappalainen, Pekka, Goode, Bruce L.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869398/
https://ncbi.nlm.nih.gov/pubmed/20362448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.03.026
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