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ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC

Advances in human genetics are leading to the discovery of new disease-causing mutations at a remarkable rate. Many such mutations, however, occur in genes that encode for proteins of unknown function, which limits our molecular understanding of, and ability to devise treatments for, human disease....

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Hlavní autoři: Blankman, Jacqueline L., Long, Jonathan Z., Trauger, Sunia A., Siuzdak, Gary, Cravatt, Benjamin F.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557017/
https://ncbi.nlm.nih.gov/pubmed/23297193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217121110
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