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Phase I trial of weekly trabectedin (ET-743) and gemcitabine in patients with advanced solid tumors
PURPOSE: To determine the maximum tolerated dose (MTD) of trabectedin plus gemcitabine administered on a weekly schedule in patients with advanced solid tumors. METHODS: Patients with ECOG performance status 0–1 and adequate organ function were enrolled. On days 1, 8, and 15 of a 28-day cycle, patie...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556988/ https://ncbi.nlm.nih.gov/pubmed/18379785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-008-0733-7 |
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