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Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival

BACKGROUND: Glioblastoma multiforme, the most common type of primary brain tumor in adults, is driven by cells with neural stem (NS) cell characteristics. Using derivation methods developed for NS cells, it is possible to expand tumorigenic stem cells continuously in vitro. Although these glioblasto...

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Détails bibliographiques
Auteurs principaux: Engström, Pär G, Tommei, Diva, Stricker, Stefan H, Ender, Christine, Pollard, Steven M, Bertone, Paul
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556652/
https://ncbi.nlm.nih.gov/pubmed/23046790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm377
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