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Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion

Nature has exploited medium-sized 8- to 11-membered rings in a variety of natural products to address diverse and challenging biological targets. However, due to the limitations of conventional cyclization-based approaches to medium-ring synthesis, these structures remain severely underrepresented i...

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Detalhes bibliográficos
Main Authors: Bauer, Renato A., Wenderski, Todd A., Tan, Derek S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556477/
https://ncbi.nlm.nih.gov/pubmed/23160003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1130
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