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A happy medium: the synthesis of medicinally important medium-sized rings via ring expansion

Medium-sized rings have much promise in medicinal chemistry, but are difficult to make using direct cyclisation methods. In this minireview, we highlight the value of ring expansion strategies to address this long-standing synthetic challenge. We have drawn on recent progress (post 2013) to highligh...

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Bibliografische gegevens
Gepubliceerd in:Chem Sci
Hoofdauteurs: Clarke, Aimee K., Unsworth, William P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society of Chemistry 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152702/
https://ncbi.nlm.nih.gov/pubmed/34122787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc00568a
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