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A Review of Human Pluripotent Stem Cell-Derived Cardiomyocytes for High-Throughput Drug Discovery, Cardiotoxicity Screening and Publication Standards

Drug attrition rates have increased in past years, resulting in growing costs for the pharmaceutical industry and consumers. The reasons for this include the lack of in vitro models that correlate with clinical results, and poor preclinical toxicity screening assays. The in vitro production of human...

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Autors principals: Mordwinkin, Nicholas M., Burridge, Paul W., Wu, Joseph C.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556463/
https://ncbi.nlm.nih.gov/pubmed/23229562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-012-9423-2
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