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Comprehensive Interrogation of Natural TALE DNA Binding Modules and Transcriptional Repressor Domains

Transcription activator-like effectors (TALE) are sequence-specific DNA binding proteins that harbor modular, repetitive DNA binding domains. TALEs have enabled the creation of customizable designer transcriptional factors and sequence-specific nucleases for genome engineering. Here we report two im...

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Detalhes bibliográficos
Main Authors: Cong, Le, Zhou, Ruhong, Kuo, Yu-chi, Cunniff, Margaret, Zhang, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556390/
https://ncbi.nlm.nih.gov/pubmed/22828628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1962
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